## Background: Inhibition of apoptosis, or programmed cell death, may be critical both in the development of cancer and in determining response to therapy. the authors examined the expression of two related apoptotic inhibitors, bcl-2 and bcl-xl, in pretreatment biopsies from a series of 42 patient
Expression of p53 protein and the apoptotic regulatory molecules Bcl-2, Bcl-XL, and Bax in locally advanced squamous cell carcinoma of the lung
โ Scribed by Shabnam, Mir Snober; Srinivasan, Radhika; Wali, Anjlina; Majumdar, Siddhartha; Joshi, Kusum; Behera, Digambar
- Book ID
- 119318891
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 297 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0169-5002
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## Background Proteins regulating the cell cycle and cell death are frequently abnormally expressed in cancer. Several of these, particularly p53 and Bclโ2, have been widely suggested as possible prognostic markers in diverse human malignancies. Their role in predicting outcome in squa
Samples of normal esophageal squamous epithelium (n โซุโฌ 10), severe squamous cell dyplasia (n โซุโฌ 22), carcinoma in situ (n โซุโฌ 15), invasive squamous cell carcinoma (n โซุโฌ 172), lymph-node metastasis (n โซุโฌ 21) and 2 permanent esophageal squamous cell carcinoma cell lines were analyzed immunohistoc