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The Involvement of Activated ras Genes in Determining the Transformed Phenotype

✍ Scribed by Marshall, C. J.; Vousden, K.; Ozanne, B.


Book ID
120142104
Publisher
The Royal Society
Year
1985
Tongue
English
Weight
534 KB
Volume
226
Category
Article
ISSN
0080-4649

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## Abstract Recent studies have shown that the proliferation of some tumor cells is dependent on autocrine growth loops that require amidated autocrine growth factors. Peptidylglycine α‐monooxygenase (PAM) is required for amidation of these growth factors and, therefore, this enzyme is an attractiv