The Intramolecular Heck Reaction
✍ Scribed by J. T. Link
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 47 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract A novel access to α‐methylene‐γ‐sultams __via__ the intramolecular Heck reaction of α‐bromovinylsulfonamides derived from allylic amines is reported. These heterocycles are potent Michael acceptors towards sulfur nucleophiles.
## Abstract The syntheses of paullone (**1a**) and three paullone derivatives, including a sulfur analogue (**2a**), a tricyclic derivative (**2b**), and a ring‐enlarged variant (**2c**), are described, Pd‐catalyzed intramolecular __Heck__ reaction being the key step. The kinase‐inhibitory properti