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Synthesis of Sultams by Intramolecular Heck Reaction

✍ Scribed by Sandra Merten; Roland Fröhlich; Olga Kataeva; Peter Metz


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
170 KB
Volume
347
Category
Article
ISSN
1615-4150

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✦ Synopsis


Abstract

A novel access to α‐methylene‐γ‐sultams via the intramolecular Heck reaction of α‐bromovinylsulfonamides derived from allylic amines is reported. These heterocycles are potent Michael acceptors towards sulfur nucleophiles.


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