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The Interaction of α-Thalassaemia and Haemoglobin G Philadelphia

✍ Scribed by R. F. Rieder; D. H. Woodbury; D. L. Rucknagel


Book ID
114708394
Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
505 KB
Volume
32
Category
Article
ISSN
0007-1048

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Is haemoglobin Gα Philadelphia linked to
✍ C. Politis-Tsegos; A. Lang; R. Stathopoulou; H. Lehmann 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 426 KB

The question, "Is Hb G alpha Philadelphia linked to alpha-thalassaemia?" was first posed because the abnormal haemoglobin is found in heterozygotes at a concentration greater than 25%, the proportion predicted from a 4 alpha-chain gene model. Globin chain biosynthesis was studied in a West Indian fa