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The interaction of Ras with GTPase-activating proteins

โœ Scribed by Alfred Wittinghofer; Klaus Scheffzek; Mohammad Reza Ahmadian

Book ID
117107458
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
621 KB
Volume
410
Category
Article
ISSN
0014-5793

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Ras interaction with the GTPase-activati
Ras interaction with the GTPase-activating protein (GAP)
โœ Michael D. Schaber; Victor M. Garsky; Douglas Boylan; Wendy S. Hill; Edward M. S ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 946 KB

Biologically active forms of Ras complexed to GTP can bind to the GTPase-activating protein (GAP), which has been implicated as possible target of Ras in mammalian cells. In order to study the structural features of Ras required for this interaction, we have evaluated a series of mutant ras proteins