Abnormal expression of BRCA1 and BRCA1-i
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Kiyotsugu Yoshikawa; Tomoko Ogawa; Richard Baer; Hiromichi Hemmi; Kazuo Honda; A
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Article
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2000
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John Wiley and Sons
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French
β 513 KB
Breast cancer is one of the most common malignancies among women. The molecular mechanisms involved in breast carcinogenesis, however, remain to be elucidated. Although somatic mutation of BRCA1 is rare, BRCA1 protein expression is reduced in about 30% of sporadic breast carcinomas (Yoshikawa et al.