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The initiation of liver development is dependent on Foxa transcription factors

✍ Scribed by Lee, Catherine S.; Friedman, Joshua R.; Fulmer, James T.; Kaestner, Klaus H.


Book ID
109894332
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
301 KB
Volume
435
Category
Article
ISSN
0028-0836

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A network of liver-enriched transcription factors controls differentiation and morphogenesis of the liver. These factors interact via direct, feedback, and autoregulatory loops. Previous work has suggested that hepatocyte nuclear factor (HNF)-6/OC-1 and HNF-3alpha/FoxA1 participate coordinately in t