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The inhibition of DNA repair by aphidicolin or cytosine arabinoside om X-irradiated normal and xeroderma pigmentosum fibroblasts

โœ Scribed by Raymond Waters; Kevin Crocombe; Razmik Mirzayans

Book ID
113192302
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
279 KB
Volume
94
Category
Article
ISSN
0027-5107

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โœ James E. Cleaver ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 902 KB

Inhibition of the gap-filling, polymerizing step of excision repair by 1-0-D-arabinofuranosylcytosine (ara-C) after irradiation with ultraviolet light in human diploid fibroblasts resulted in the formation of persistent DNA strand breaks in G,, G,, and plateau phase cells, but not in S phase cells.