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The Influence of Vehicles on the Action of Drugs*

โœ Scribed by Hazleton, Lloyd W. ;Hellerman, Rebecca C.

Publisher
Elsevier
Year
1946
Weight
683 KB
Volume
35
Category
Article
ISSN
0095-9553

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On the influence of protein binding on p
On the influence of protein binding on pharmacological activity of drugs
โœ Leonid M. Berezhkovskiy ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 204 KB ๐Ÿ‘ 1 views

The effect of variable protein binding (taken as independent parameter) on pharmacological activity of drugs is considered in terms of the exposure or the steady state concentration of unbound drug at targeted tissue. Based on the application of the parallel tube or dispersion models it is shown tha