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The influence of surface microroughness and hydrophilicity of titanium on the up-regulation of TGFβ/BMP signalling in osteoblasts.

✍ Scribed by J. Vlacic-Zischke; S.M. Hamlet; T. Friis; M.S. Tonetti; S. Ivanovski

Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
275 KB
Volume
32
Category
Article
ISSN
0142-9612

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## Abstract This study investigated the combined application of Transforming Growth Factor β‐1 (TGFβ‐1) and Bone Morphogenetic Protein‐2 (BMP‐2) to stimulate osteogenic expression __in vitro__. TGFβ‐1 and BMP‐2 fulfill specific roles in the formation of new bone. COLLOSS® E, a bone‐derived collagen