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The influence of serum components on the growth and mutation of Chinese hamster cells in medium containing aminopterin

โœ Scribed by A.R. Peterson; Hazel Peterson; Charles Heidelberger

Book ID
116036802
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
558 KB
Volume
24
Category
Article
ISSN
0027-5107

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## Abstract The genetic mechanisms determining the ability of transformed cells to grow in a medium with a low serum content (ser^+^) were studied in a clone of Chinese hamster cells with normal serum requirements. The fluctuation test has shwon that serum independence occurs as a random spontaneou