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The influence of recombinant human insulin-like growth factor-I (rhIGF-I) on cell growth and cytotoxicity of drugs in childhood rhabdomyosarcoma cell lines and xenograft models

โœ Scribed by Corrie E.M. Gidding; Glen S. Germain; Michael B. Dilling; Tiny G. J. Meeuwsen-de Boer; Richard A. Ashmun; Siebold S. N. de Graaf; Karen A. Veverka; Willem A. Kamps; Peter J. Houghton


Publisher
Springer
Year
2000
Tongue
English
Weight
493 KB
Volume
45
Category
Article
ISSN
0344-5704

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We examined the effects of recombinant human insulin-like growth factor I (IGF-I) and insulin on the plasma amino acid (AA) profile and leucine kinetics in eight normal subjects. IGF-I was infused at 52 pmol. kg -1. min -1, in combination with prime-continuous [1-14C] leucine infusion, to obtain ste