## Abstract The insulinβlike growth factor (IGF) system is a key regulator of cell growth, survival and differentiation, and these functions are coβmodulated by other growth factors including fibroblast growth factorβ2 (FGFβ2). To investigate IGF/FGF interactions in neuronal cells, we employed neur
Insulin-like growth factor-I induces the phosphorylation and nuclear exclusion of forkhead transcription factors in human neuroblastoma cells
β Scribed by T. S. Schwab; B. B. Madison; A. R. Grauman; E. L. Feldman
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 716 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1360-8185
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Human breast cancer MCFβ7 cells, growthβarrested by serum starvation, were stimulated with recombinant human insulinlike growth factorβ1 (IGFβI). An increase in DNA synthesis was induced 20 hr later, which was as effective as that induced by serum. The increase in DNA synthesis was sign
Neuroblastoma is a childhood tumor of the peripheral nervous system that remains largely uncurable by conventional methods. Mannitol induces apoptosis in neuroblastoma cell types and insulin-like growth factor I (IGF-I) protects these cells from hyperosmotic-induced apoptosis by affecting apoptosis-
Recently, a family of growth factors has been described that activates erbB-2 receptors. These factors, known as the neu differentiation factors (NDF) or heregulins (HRG), induce tyrosine phosphorylation of erbB-2 receptors as a result of their direct interaction with either erbB-3 or erbB-4 recepto
The growth regulation of human diploid fibroblasts by platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin-like growth factor I (IGF-I) (somatomedin C), dexamethasone, and transferrin was investigated in a serumfree, chemically defined culture system. Cell-cycle kinetic para