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The influence of potassium on the electrical and mechanical activity of the guinea pig ureter

โœ Scribed by Hendrickx, H. ;Vereecken, R.L. ;Casteels, R.

Publisher
Springer
Year
1975
Tongue
English
Weight
304 KB
Volume
3
Category
Article
ISSN
0300-5623

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โœฆ Synopsis

Increase of the external K+ concentration depolarises the ureteral muscle membrane and induces, after a transient period of increased spontaneous activity, a tonic contraction. Tetraethylammonium, in concentrations normally required for ganglion blocking activity, does not influence the ureteral activity, but in higher doses it prolonges the duration of the action potential several times and increases the intraluminal pressure. Ouabain has only an inhibitory effect on the guinea pig ureter.

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