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The influence of medium composition on the maintenance of cytochrome P-450, glutathione content and urea synthesis: a comparison of rat and sheep primary hepatocyte cultures

✍ Scribed by Patricia Watts; Mark D. Smith; Ian Edwards; Victor Zammit; Vivienne Brown; Helen Grant

Book ID: 119135826
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 926 KB
Volume: 23
Category: Article
ISSN: 0168-8278
DOI: 10.1016/0168-8278(95)80069-7

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## Abstract Four β‐glycosides of flavonoligan silybin, i.e. silybin β‐galactoside, silybin β‐glucoside, silybin β‐maltoside, silybin β‐lactoside were synthesized in order to improve silybin water solubility and bioavailability (Křen et al., J Chem Soc, Perkin Trans 1, 2467–2474, 1997). The presente