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THE INFLUENCE OF LIDOCAINE AND VERAPAMIL ON HAEMODYNAMIC PARAMETERS AFTER INTRAVENOUS ADMINISTRATION OF MIDAZOLAM IN RABBITS

โœ Scribed by A. WIKTOROWSKA; J. OWCZAREK; D. ORSZULAK-MICHALAK

Book ID
118770659
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
256 KB
Volume
39
Category
Article
ISSN
1043-6618

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Deacetyl diltiazem (M 1 ) is a major metabolite of the widely used calcium antagonist diltiazem (DTZ). In order to study the pharmacokinetic and haemodynamic effects of this metabolite, M 1 was administered as a single 5 mg kg -1 dose intravenously (iv) to New Zealand white rabbits (n = 5) via a mar