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Effects of verapamil on etoposide pharmacokinetics after intravenous and oral administration in rats

โœ Scribed by Yong-Ji Piao; Xiuguo Li; Jun-Shik Choi


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
624 KB
Volume
33
Category
Article
ISSN
0378-7966

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The pharmacokinetics of the anticholinergic drug ethopropazine (ET) have been studied in the rat after intravenous (i.v.) and oral administration. After i.v. doses of 5 and 10 mg/kg ET HCl, mean +/- S.D. plasma AUC were 9836 +/- 2129 (n = 4 rats) and 13096 +/- 4186 ng h/mL (n = 5 rats), respectively