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The influence of heat capacity assumptions on the estimation of solubility parameters from solubility data

✍ Scribed by Neau, Steven H.; Flynn, Gordon L.; Yalkowsky, Samuel H.

Book ID
123565068
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
486 KB
Volume
49
Category
Article
ISSN
0378-5173

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The transition temperature, T t , of polymorphs is estimated from both their heats of solution and solubilities (or intrinsic dissolution rates) determined at any one temperature (e.g., ambient). At a given temperature, T, the enthalpy difference, DH, between polymorphs, I and II, is equal to the di