The influence of formulation components on the aerosolisation properties of spray-dried powders
β Scribed by Naumana R. Rabbani; Peter C. Seville
- Book ID
- 113691051
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 445 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0168-3659
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The physicochemical properties of two forms of spray dried bovine serum albumin (BSA) have been investigated using particle sizing, surface energy measurement, atomic force microscopy (AFM) and colloid probe microscopy. The BSA powder had similar particle size distributions and surface energy but si
## Abstract ## Background Pulmonary delivery of gene therapy offers the potential for the treatment of a range of lung conditions, including cystic fibrosis, asthma and lung cancer. Sprayβdrying may be used to prepare dry powders for inhalation; however, aerosolisation of such powders is limited,