The influence of duration of intravenous infusion of an acute dose on plasma concentrations of cimetidine
β Scribed by D. J. Morgan; D. A. Uccellini; K. Raymond; G. W. Mihaly; D. B. Jones; R. A. Smallwood
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 652 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0031-6970
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π SIMILAR VOLUMES
The pharmacokinetics and pharmacodynamics of bumetanide were evaluated after intravenous (i.v.) administration of the same total dose of bumetanide in different lengths of infusion times, 10 s (treatment I), 1 h (treatment 11), and 4 h (treatment 111) to rabbits. The fluid loss in urine was immedia
## Abstract Plasma concentrationβtime data resulting from constant rate intravenous infusion may be analysed in two ways: Samples may be collected both during and after infusion and fit to an infusion model. Samples may be collected after infusion is complete and the data may be fit as an i.v. bo