The influence of CGS 16949A on peripheral aromatisation in breast cancer patients
✍ Scribed by Lønning, PE; Jacobs, S; Jones, A; Haynes, B; Powles, T; Dowsett, M
- Book ID
- 109836570
- Publisher
- Nature Publishing Group
- Year
- 1991
- Tongue
- English
- Weight
- 915 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0007-0920
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## Background: Fadrozole hydrochloride (cgs 16949a) is a highly potent, nonsteroidal aromatase inhibitor that significantly lowers estrogen levels in postmenopausal women and can be effective therapy for patients with advanced hormone-dependent breast carcinoma. circulating estradiol, estrone, and
## Abstract The end results of therapy of 1,358 breast cancer patients were studied. Anaesthesia was performed by ether‐nitrogen‐oxygen (554 cases) or halothane‐nitrogen‐oxygen (804 cases) mixture with addition of oxygen. The method of Holstead was employed in all cases. A comparison of groups of p