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Influence of aminoglutethimide on plasma oestrogen levels in breast cancer patients on 4-hydroxyandrostenedione treatment

✍ Scribed by P. E. Lønning; M. Dowsett; A. Jones; D. Ekse; S. Jacobs; F. McNeil; D. C. Johannessen; T. J. Powles

Publisher
Springer US
Year
1992
Tongue
English
Weight
643 KB
Volume
23
Category
Article
ISSN
0167-6806

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The influence of a graded dose schedule of aminoglutethimide on the disposition of the optical enantiomers of warfarin in patients with breast cancer
✍ P. E. Lønning; P. M. Ueland; S. Kvinnsland 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 508 KB

The pharmacokinetics of the optical enantiomers of warfarin (R-warfarin and S-warfarin) were investigated in patients treated for breast cancer with aminoglutethimide (AG). The patients received 125 mg AG b.i.d. (i.e., low-dosage regimen); 250 mg AG q.i.d. together with cortisone acetate (i.e. high-