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The induction of smooth muscle α actin in a transformed rat cell line suppresses malignant properties in vitro and in vivo

✍ Scribed by Mitsuse Okamoto-Inoue; Shinji Kamada; Genki Kimura; Shun'ichiro Taniguchi

Book ID
117469515
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
534 KB
Volume
142
Category
Article
ISSN
0304-3835

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## Abstract We conducted an experiment to determine whether expression of transforming growth factor‐α (TGF‐α) enhances tumorigenicity in a low‐tumorigenicity rat bladder carcinoma cell line and whether it is sufficient to induce a tumorigenic phenotype in a nontumorigenic rat bladder cell line. D4