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In vitro proliferation and in vivo malignancy of cell lines simultaneously derived from a chemically-induced heterogeneous rat mammary tumor

✍ Scribed by Fausto Tagliaferri; Laura Teodori; Maria Giovanna Valente; Francesco Stipa; Alessandra Cucina; Wolfgang Göhde; Dario Coletti; Piero Alo'; Sergio Stipa

Book ID
115044786
Publisher
Society for In Vitro Biology
Year
2000
Tongue
English
Weight
421 KB
Volume
36
Category
Article
ISSN
1475-2689

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✍ J. Belehradek Jr.; J. L. Biedler; M. Thonier; G. Barski 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 French ⚖ 761 KB

## Abstract The tumorigenic EPO clonal cell line, derived from a methylcholanthrene‐induced murine sarcoma, was exposed to increasing concentrations of actinomycin D and gave rise to a subline, resistant to 0.02 μg of actinomycin D per ml of medium, which was designated EPO/ADj. Drug resistance was