๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The induction of lysis of renal cell carcinoma cells by bispecific monoclonal antibodies

Book ID
123388738
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
148 KB
Volume
1
Category
Article
ISSN
1043-4666

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Induction of tumor-cell lysis by bi-spec
Induction of tumor-cell lysis by bi-specific monoclonal antibodies recognizing renal-cell carcinoma and cd3 antigen
โœ J. Van Duk; S. O. Warnaar; J. D. H. Van Eendenburg; M. Thienpont; E. Braakman; J ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 644 KB

## Bi -specific monoclonal antibodies (MAbs) were developed by somatic hybridization of 2 mouse hybridomas, one producing MAb against the G250 renal-cell carcinoma (RCC)-associated antigen and the other against the T-cell antigen CD3 (OKT3). The dual specificity of the hybrid MAb produced by these

Trifunctional bispecific antibodyโ€“induce
Trifunctional bispecific antibodyโ€“induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tract
โœ Silke S. Gronau; Michael Schmitt; Bernard Thess; Peter Reinhardt; Markus Wiesnet ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 598 KB

## Abstract ## Background. The trifunctional bispecific antibody Removab (tbAB) bridges and activates CD3 positive T cells to EpCAM on carcinoma cells and simultaneously binds to an accessory immuneโ€cell inducing tumor cell lysis. tbABโ€induced tumor cytotoxicity was assessed in an autologous human

Two-step radio-immunotargeting of renal-
Two-step radio-immunotargeting of renal-cell carcinoma xenografts in nude mice with anti-renal-cell-carcinoma X anti-DTPA bispecific monoclonal antibodies
โœ Marion H. G. C. Kranenborg; Otto C. Boerman; Jeannette C. Oosterwijk-Wakka; Mirj ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 148 KB ๐Ÿ‘ 2 views

The specificity of antibodies offers unique opportunities to target tumors with radionuclides. However, due to the slow clearance of radiolabeled antibody, relatively high background is observed in non-target organs. Pre-targeting protocols using bispecific monoclonal antibodies (bsMAbs) and radiola