## Abstract Heme oxygenaseβ1 (HOβ1) is known as a stressβinducible protein and functions as an antioxidant enzyme. It has been shown that HOβ1 is induced rapidly by a variety of chemical and physical stimuli. However, little is known about the induction of cellular signaling events after cell expos
The induction of cytotoxicity, oxidative stress, and genotoxicity by root canal sealers in mammalian cells
β Scribed by Carlos Henrique Ribeiro Camargo; Samira Esteves Afonso Camargo; Marcia Carneiro Valera; Karl-Anton Hiller; Gottfried Schmalz; Helmut Schweikl
- Book ID
- 116942691
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 631 KB
- Volume
- 108
- Category
- Article
- ISSN
- 1528-395X
No coin nor oath required. For personal study only.
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## Abstract Endodontic sealers frequently are placed in direct contact with living tissues. Thus root canal sealers should have good biocompatibility. However, the pathobiologic effects, especially genotoxicity, of various root canal sealers widely used in dentistry have not been studied systematic
## Abstract An important requirement for a rootβcanal sealer is biologic compatibility; most evaluations have focused on general toxicological and local tissue irritating properties. There is only scant information about mutagenicity or carcinogenicity testing for rootβcanal sealer. It has been sho