The inactivation of thiamin by Bracken(Pteris aquilina)
β Scribed by And, Brynmor Thomas ;Walker, H. F.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1949
- Weight
- 487 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0368-4075
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β¦ Synopsis
Abstract
The antiβthiamin effect of bracken, noted by Weswig, Freed and Haeg, has been confirmed. Rats on a diet containing 40% bracken, and providing adequate amounts of thiamin, lost weig it and died within thirty days. Control groups receiving large supplementary doses of thiamin made continuous increases in bodyweight. The hearts and livers of rats which had succumbed to a brackenβcontaining diet were shown to be of abnormally low thiamin content. An incubation technique developed by the authors, showed that bracken had the capacity to inactivate large amounts of vitamin.
π SIMILAR VOLUMES
A procedure for the rapid, sensitive, and direct measurement of thiamin pyrophosphate (TPP) in erythrocytes using high-performance liquid chromatography (HPLC) is described. Human erythrocyte TPP levels from 17 normal healthy adults had a mean value of 123 + 27 @ml packed erythrocytes, ranging from