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The in vivo synthesis of plant sesquiterpenes by Escherichia coli

✍ Scribed by Vincent J.J. Martin; Yasuo Yoshikuni; Jay D. Keasling

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
305 KB
Volume
75
Category
Article
ISSN
0006-3592

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## Abstract __Two metabolically engineered__ Escherichia coli __strains have been constructed to produce the carbohydrate moieties of gangliosides GM2 (GalNAc__Ξ²__‐4(NeuAc__Ξ±__‐3)Gal__Ξ²__‐4Glc; Gal=galactose, Glc=glucose, Ac=acetyl) and GM1 (Gal__Ξ²__‐3GalNAc__Ξ²__‐4(NeuAc__Ξ±__‐3)Gal__Ξ²__‐4Glc. The G