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The in vitro transport of model thiodipeptide prodrugs designed to target the intestinal oligopeptide transporter, PepT1

โœ Scribed by Foley, David; Pieri, Myrtani; Pettecrew, Rachel; Price, Richard; Miles, Stephen; Lam, Ho Kam; Bailey, Patrick; Meredith, David

Book ID
118274716
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
165 KB
Volume
7
Category
Article
ISSN
1477-0520

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Extracellular glucose concentration alte
Extracellular glucose concentration alters functional activity of the intestinal oligopeptide transporter (PepT-1) in Caco-2 cells
โœ Vanessa M. D'Souza; Donna J. Buckley; Arthur R. Buckley; Giovanni M. Pauletti ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 133 KB

The objective of this study was to determine the effect of different cell culture media glucose concentrations on the functional activity of PepT-1 in Caco-2 cells. Uptake kinetics of Gly-Sar into Caco-2 cells that were maintained in iso-osmotic media containing 25 or 5.5 mM glucose were determined