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The Importance of IGHV Mutational Status in del(11q) and del(17p) Chronic Lymphocytic Leukemia

✍ Scribed by Douglas E. Gladstone; Amanda Blackford; Eunpi Cho; Lode Swinnen; Yvette Kasamon; Christopher D. Gocke; Constance A. Griffin; Javier Bolaños-Meade; Richard J. Jones

Book ID
119219020
Publisher
Elsevier
Year
2012
Tongue
English
Weight
345 KB
Volume
12
Category
Article
ISSN
2152-2650

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✍ Sandra Quijano; Antonio López; Ana Rasillo; José María Sayagués; Susana Barrena; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 571 KB

## Abstract B‐cell chronic lymphocytic leukemia (B‐CLL) is a well‐defined clinical entity with heterogeneous molecular and cytogenetic features. Here, we analyze the impact of trisomy 12, del(13q), del(17p), and del(11q) as determined by interphase fluorescence in situ hybridization analysis of pur