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The importance of gene-centring microarray data

✍ Scribed by Therese Sørlie; Eldrid Borgan; Simen Myhre; Hans Kristian Vollan; Hege Russnes; Xi Zhao; Gro Nilsen; Ole Christian Lingjærde; Anne-Lise Børresen-Dale; Einar Rødland

Book ID
117785430
Publisher
The Lancet
Year
2010
Tongue
English
Weight
95 KB
Volume
11
Category
Article
ISSN
1470-2045

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✍ WENTIAN LI; YANING YANG 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 264 KB

Using a measure of how differentially expressed a gene is in two biochemically/phenotypically different conditions, we can rank all genes in a microarray dataset. We have shown that the falling-off of this measure (normalized maximum likelihood in a classification model such as logistic regression)