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The importance of gene-centring microarray data – Authors' reply

✍ Scribed by Britta Weigelt; Alan Mackay; Rachael Natrajan; David SP Tan; Mitch Dowsett; Alan Ashworth; Jorge S Reis-Filho

Book ID
117785439
Publisher
The Lancet
Year
2010
Tongue
English
Weight
83 KB
Volume
11
Category
Article
ISSN
1470-2045

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Using a measure of how differentially expressed a gene is in two biochemically/phenotypically different conditions, we can rank all genes in a microarray dataset. We have shown that the falling-off of this measure (normalized maximum likelihood in a classification model such as logistic regression)