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The importance of extended conformations and, in particular, the PII conformation for the molecular recognition of peptides

✍ Scribed by Giuliano Siligardi; Alex F. Drake

Publisher
Wiley (John Wiley & Sons)
Year
1995
Tongue
English
Weight
1020 KB
Volume
37
Category
Article
ISSN
0006-3525

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πŸ“œ SIMILAR VOLUMES

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Interrelationships among the coupling between the amide I vibrations of peptide groups, the wavenumber A-E 1 di †erence of the amide I mode and the conformation of helical polypeptide chains were examined theoretically. Ab initio molecular orbital (MO) calculations were performed for a glycine dipep

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## Synopsis Efforts to understand the chemical-physical basis for peptide hormone and neurotransmitter action requires integration of conformational parameters and biological properties. Since most peptide hormones are conformationally flexible, the question arises as to which of the manifold of c