๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Conformational and topographical considerations in the design of biologically active peptides

โœ Scribed by Victor J. Hruby


Publisher
Wiley (John Wiley & Sons)
Year
1993
Tongue
English
Weight
833 KB
Volume
33
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Conformational and dynamic consideration
โœ Victor J. Hruby; Henry I. Mosberg; Tomi K. Sawyer; James J. Knittel; Todd W. Roc ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 812 KB

## Synopsis Efforts to understand the chemical-physical basis for peptide hormone and neurotransmitter action requires integration of conformational parameters and biological properties. Since most peptide hormones are conformationally flexible, the question arises as to which of the manifold of c

The role of proline in the proteolytic r
โœ A. Yaron ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 527 KB

Specificity studies of the enzymatic hydrolysis of proline-containing peptides give further evidence of the unique nature of the Xaa-Pro bond and indicate its role in the limited proteolysis as a structural element protecting the N-terminal chain end. A sensitive, highly specific fluorogenic assay w

Design and conformation of non-Aib synth
โœ G. Molle; H. Duclohier; J.-Y. Dugast; G. Spach ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 635 KB

Analogues of alamethicin, a 20-mer amphipathic helical peptide with ionophore activity, in the sequence of which all Aib residues were substituted by Ala (Al) or Leu (Ll), were synthesized by the solid phase method, purified by high performance liquid chromatography and characterized by fast atomic