Human UDP-glucuronosyltransferase (UGT)1
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Jocelyn Trottier; Mélanie Verreault; Susan Grepper; Didier Monté; Julie Bélanger
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Article
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2006
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John Wiley and Sons
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English
⚖ 1003 KB
Chenodeoxycholic acid (CDCA) is a liver-formed detergent and plays an important role in the control of cholesterol homeostasis. During cholestasis, toxic bile acids (BA) accumulate in hepatocytes causing damage and consequent impairment of their function. Glucuronidation, a conjugation reaction cata