Interactions between human UDP-glucurono
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Ryoichi Fujiwara; Miki Nakajima; Shingo Oda; Hiroyuki Yamanaka; Shin-ichi Ikushi
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Article
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2010
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John Wiley and Sons
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English
β 314 KB
Glucuronidation catalyzed by UDP-glucuronosyltransferase (UGT) enzymes is an important pathway in the metabolism of drugs as well as environmental chemicals. In this study, protein-protein interactions between human UGT2B7 and UGT1As and their effects on the enzymatic activities were investigated us