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The impact of tumour volume and other characteristics on uptake of radiolabelled monoclonal antibodies in tumour tissue of head and neck cancer patients

✍ Scribed by Remco de Bree; Dirk J. Kuik; Jasper J. Quak; Jan C. Roos; Michiel W. M. van den Brekel; Jonas A. Castelijns; Frank W. van Wagtendonk; Henri Greuter; Gordon B. Snow; Guus A. M. S. van Dongen


Publisher
Springer
Year
1998
Tongue
English
Weight
41 KB
Volume
25
Category
Article
ISSN
0340-6997

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## Abstract This study examined the sensitivity and specificity of serum auto‐antibodies to p53 protein as a non‐invasive marker of p53 genetic alterations or protein accumulation in lung cancer cases. A sensitive ELISA to detect serum p53 antibodies was developed and used to examine sera from 186