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The impact of roller compaction and tablet compression on physicomechanical properties of pharmaceutical excipients

✍ Scribed by Iyer, Raman Mahadevan; Hegde, Shridhar; DiNunzio, James; Singhal, Dharmendra; Malick, Waseem

Book ID
120821497
Publisher
Informa plc
Year
2013
Tongue
English
Weight
606 KB
Volume
19
Category
Article
ISSN
1083-7450

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A quality-by-design study examining the impact of variability in excipient material properties on the quality attributes of an immediate release tablet was performed. A literature review and risk analysis identified particle size of microcrystalline cellulose (MCC), spray-dried lactose (SDL), and ma