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Roller compaction of different pseudopolymorphic forms of Theophylline: Effect on compressibility and tablet properties

✍ Scribed by Ervina Hadžović; Gabriele Betz; Šeherzada Hadžidedić; Silvia Kocova El-Arini; Hans Leuenberger


Book ID
108147123
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
493 KB
Volume
396
Category
Article
ISSN
0378-5173

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Heckel analysis, tablet tensile strength, and indentation hardness were determined for a series of sieved and roller compacted microcrystalline cellulose mixtures under both unlubricated and lubricated conditions with magnesium stearate. These results have been used to evaluate the loss of reworkabi