The impact of regulatory T cells on carcinogen-induced sarcogenesis
β Scribed by Betts, G; Twohig, J; Van den Broek, M; Sierro, S; Godkin, A; Gallimore, A
- Book ID
- 109999185
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 167 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0007-0920
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract There has been accumulating evidence that CD4^+^CD25^+^ FoxP3 expressing regulatory T cells (Treg) are highly concentrated in tumors, thereby fostering an immuneβprivileged microenvironment. Some studies have shown that Tβcell receptor (TCR) stimulation can convert conventional T cells
## Abstract The gut is home to a large number of Treg, with both CD4^+^ CD25^+^ Treg and bacterial antigenβspecific Tr1 cells present in normal mouse intestinal lamina propria. It has been shown recently that intestinal mucosal DC are able to induce Foxp3^+^ Treg through production of TGFβΞ² plus re