Orientals consisting of Japanese, Chinese, Koreans, and Filipinos are clearly at higher risk for cleft lip with or without cleft palate [CL(P)] than whites, Puerto Ricans, and Hawaiians/part-Hawaiians in Hawaii. Using the model of diallele cross, CL(P) incidences in incrosses and outcrosses involvin
The impact of participation in genetic research for families with cleft lip with and without cleft palate: a qualitative study
β Scribed by Donoghue, Lynley J.; Sahhar, Margaret A.; Savarirayan, Ravi; Raj, Supriya; Kilpatrick, Nicky M.; Forrest, Laura E.
- Book ID
- 121557515
- Publisher
- Springer-Verlag
- Year
- 2014
- Tongue
- English
- Weight
- 211 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1868-310X
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Nonsyndromic cleft lip with or without cleft palate (CL/P) is a common congenital malformation affecting about 1/1,000 caucasian infants. Although the familial clustering of CL/P has been studied thoroughly, estimation of recurrence risk for genetic counseling purposes can be difficult. A survey was
The identification of several putative susceptibility loci for nonsyndromic cleft lip with or without cleft palate (CL f P) has sparked a renewed interest in the genetics of this condition. However, prior to undertaking linkage studies for complex traits such as CL f P it is desirable to have some u
## Abstract Nonβsyndromic cleft lip with/without cleft palate (CL/P) is a common, usually nonβfatal birth defect of complex etiology. Several segregation analyses have demonstrated that genetic factors are important in the pathogenesis of CL/P, most likely through the interaction of several genes o