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Survey of genetic counselors and clinical geneticists regarding recurrence risks for families with nonsyndromic cleft lip with or without cleft palate

✍ Scribed by Wyszynski, Diego F.; Zeiger, Joanna; Tilli, Maddalena T.; Bailey-Wilson, Joan E.; Beaty, Terri H.

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 45 KB
Volume: 79
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19980923)79:3<184::aid-ajmg6>3.0.co;2-n

No coin nor oath required. For personal study only.

✦ Synopsis

Nonsyndromic cleft lip with or without cleft palate (CL/P) is a common congenital malformation affecting about 1/1,000 caucasian infants. Although the familial clustering of CL/P has been studied thoroughly, estimation of recurrence risk for genetic counseling purposes can be difficult. A survey was mailed to 912 board-certified genetic counselors, 542 non-board-certified genetic counselors, and 776 board-certified clinical geneticists to investigate the recurrence risks they would assign to three example families with CL/P. Responses were received from 155 (17%) board-certified genetic counselors, 36 (6.6%) non-board-certified genetic counselors, and 100 (18.5%) board-certified clinical geneticists. No major differences were found in their responses, suggesting that for these three families, geneticists would provide similar estimates of risk, regardless of their amount of experience with oral clefts patients, where they are currently employed, or their board certification status.

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