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The impact of high-dose methotrexate on intracellular 6-mercaptopurine disposition during interval therapy of childhood acute lymphoblastic leukemia

✍ Scribed by T. Adam de Beaumais; T. Dervieux; M. Fakhoury; Y. Medard; S. Azougagh; D. Zhang; K. Yakouben; E. Jacqz-Aigrain


Book ID
105993341
Publisher
Springer
Year
2009
Tongue
English
Weight
327 KB
Volume
66
Category
Article
ISSN
0344-5704

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Effects of high-dose methotrexate on the
✍ Totan, Mehmet ;Dagdemir, Ayhan ;Ak, Ali Riza ;Albayrak, Davut ;Kucukoduk, Sukru πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 85 KB

## Abstract ## Background Tromboembolic and hemorrhagic complications are significant causes of death in patients with malignancy. These are well‐known with the use of certain drugs. This study was planned to investigate whether there was any effect of high‐dose methotrexate on the hemostatic syst