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Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia

✍ Scribed by Carin W. Keuzenkamp-Jansen; Ronney A. De Abreu; Henk J. Blom; Jos P.M. Bökkerink; J.M.Frans Trijbels


Book ID
115784558
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
827 KB
Volume
51
Category
Article
ISSN
0006-2952

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## Abstract ## Background Tromboembolic and hemorrhagic complications are significant causes of death in patients with malignancy. These are well‐known with the use of certain drugs. This study was planned to investigate whether there was any effect of high‐dose methotrexate on the hemostatic syst