The impact of genotyping error on haplotype reconstruction and frequency estimation
β Scribed by Kirk, Katherine M; Cardon, Lon R
- Book ID
- 110025276
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 426 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1018-4813
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π SIMILAR VOLUMES
## Abstract Haplotype inference for tightly linked markers from general pedigrees remains a challenging problem. Only a few methods are available to efficiently and accurately estimate haplotype frequencies and reconstruct haplotypes for a large number of tightly linked markers from general pedigre
## Abstract Genomeβwide association studies may be necessary to identify genes underlying certain complex diseases. Because such studies can be extremely expensive, DNA pooling has been introduced, as it may greatly reduce the genotyping burden. Parallel to DNA pooling developments, the importance