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The immunomodulator Linomide: role in treatment and prevention of autoimmune diabetes mellitus

✍ Scribed by David J. Gross; Lola Weiss; Israel Reibstein; Gunnar Hedlund; Eva Dahlén; Micha J. Rapoport; Shimon Slavin

Book ID
117797839
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
151 KB
Volume
1
Category
Article
ISSN
1567-5769

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✍ D. J. Gross; H. Sidi; L. Weiss; T. Kalland; E. Rosenmann; S. Slavin 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 857 KB

Oral administration of the synthetic immunomodulating drug quinoline-3-carboxamide (Linomide) in the drinking water to 5-week-old female non-obese diabetic (NOD) mice resulted in complete protection from insulitis and maintenance of normal glucose tolerance for over 40 weeks (impaired glucose tolera