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The immunological properties of haptens coupled to thymus-independent carrier molecules. II. The influence of the graft-versus-host reaction on primary antibody responses to hapten-coupled polysaccharides and proteins

✍ Scribed by G. G. B. Klaus; A. J. McMichael


Publisher
John Wiley and Sons
Year
1974
Tongue
English
Volume
4
Category
Article
ISSN
0014-2980

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The immunological properties of haptens
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## Abstract Dinitrophenylated polysucrose (DNP‐Ficoll) elicits T cell‐independent IgM anti‐DNP antibody formation in mice. This antigen also elicits a heterogeneous IgG1 and IgG2 anti‐DNP response, which is operationally as T‐independent as the IgM response. However, a concomitant graft‐versus‐host

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## Abstract The antibody response to the hapten 2,4dinitrophenyl (DNP)lysine coupled to two thymus‐independent carrier molecules (pneumococcal polysaccharide SIII and levan) has been studied in mice. The characteristics of the anti‐hapten response are essentially similar to the response to the ca