The immunological classification of acute lymphoblastic leukemias
β Scribed by J. C. Brouet; M. Seligmann
- Book ID
- 102665970
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 922 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0008-543X
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In order to reduce the subjective errors in subtyping leukemic lyrnphoblasts using the French-American-British (FAB) classification, computer-assisted morphometry was used. Bone marrow smears obtained at diagnosis from 99 children with acute lymphoblastic leukemia (ALL) were analysed by this method
The blast cells of 8 patients with acute lymphatic leukemia were investigated for B-and T-cell properties. Membrane-bound immunoglobulins (B-cell marker) were not found, unexpectedly also not on the blasts of a boy with leukemic transformed lymphosarcoma. In contrast, in another patient, who died sh