Immunological cell markers on lymphoblasts of patients with acute lymphatic leukemia
β Scribed by H. U. Schwenk
- Book ID
- 104774455
- Publisher
- Springer
- Year
- 1974
- Tongue
- English
- Weight
- 933 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0340-6997
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β¦ Synopsis
The blast cells of 8 patients with acute lymphatic leukemia were investigated for B-and T-cell properties. Membrane-bound immunoglobulins (B-cell marker) were not found, unexpectedly also not on the blasts of a boy with leukemic transformed lymphosarcoma. In contrast, in another patient, who died shortly after diagnosis, the blasts of different compartments repeatedly showed T-cell properties (spontaneous rosette formation with sheep red blood cells).
π SIMILAR VOLUMES
## Abstract Eight patients with acute lymphosarcoma cell leukemia or acute lymphoblastic leukemia received infusions of plasma containing a lymphotoxic factor. The lymphotoxic factor induced a transient fall in the number of βblastβ cell forms in the peripheral blood in six of the eight patients bu